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Micro-sample processing provides biological and biochemical researchers with quick separations and clarifications. Microcentrifuges rapidly process small sample volumes, from 0.2 milliliters to 5 milliliters. Despite their small size, these devices operate at high speeds to separate components based on density or sedimentation rates.

These devices are widely used in biochemistry, clinical research and molecular biology, and some applications include protein purification, DNA or RNA isolation and quick sedimentation of cellular components. Most models have user-friendly, simple control panels that allow you to set parameters for speed, temperature and time.

Features of Microcentrifuges

The main differences between microcentrifuges and others are the device's size, suitability for handling small-volume samples and speed capabilities. It is essential to pick a microcentrifuge made from materials with chemical corrosion resistance to ensure the device is more durable and can operate safely.

Microcentrifuge Size

Compared to other centrifuges, these are smaller and more portable, making them suitable for benchtop use and allowing for more accessible transportation and relocation between labs. These features make them an ideal choice for laboratories with limited space. Their size does not limit their capabilities, as these devices have the same basic functions as their larger counterparts.

Rotor Configuration

It is essential to load the microcentrifuge correctly. Balance the sample tubes on the rotor and ensure loads have the same mass and weight and ensure they have the same center of gravity, meaning sample tubes should be the same size and weight. An unbalanced load can vibrate during centrifuge, which can damage the rotor.

These devices can feature two types of rotors, which are often interchangeable:

• Fixed-angle rotors: These rotors hold tubes at angles between 25 degrees and 40 degrees for effective sample pelleting.

• Swinging-bucket rotors: Sample tubes swing outward as the centrifugal force increases and stay horizontal to minimize the shear forces to which delicate samples are exposed compared to the force from a fixed-angle rotor.

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Speed and Capacity

Microcentrifuges are capable of high-speed configurations for rapid separations. These speeds can range from thousands to tens of thousands of RPMs and are helpful in hematology, immunology, endocrinology and microbiology.

A microcentrifuge with a higher G-force will complete separations with more efficiency. These devices typically hold sample volume sizes of 1.5 milliliters. Higher RPMs produce more heat, so it is vital to maintain a consistent temperature, as most hormones and enzymes are temperature-sensitive.

Materials and Composition

These devices are made from durable materials, allowing them to withstand high-speed centrifugation while maintaining reliability. Materials often used to manufacture microcentrifuges are:

• Plastics: Polycarbonate provides impact resistance and decent strength. Its transparency allows lab technicians to monitor the centrifugation process safely, and the rotors and rotor adapters may be made from polypropylene, which has a high chemical resistance.

• Metals: Rotor components may be made of aluminum, which is lightweight and robust. Parts of the centrifuge may be reinforced with stainless steel. This material is corrosion-resistant and strong enough to support critical structural components.

• Composite materials: Some models are made with carbon fiber, which has a high strength-to-weight ratio to the device's weight, an essential characteristic.

• Rubber or silicone: Gaskets and seals are supported by rubber and silicone to reduce device vibration and ensure proper sealing. These high-quality components withstand regular use for longevity.

Benefits of Buying Used Microcentrifuges

Purchasing a used microcentrifuge with a rotor can cut costs significantly — often helping you find equipment for 30% to 70% under new equipment prices. Buying used instruments has other advantages, such as:

• Environmental benefits: Manufacturing new equipment may involve non-environmentally friendly processes. By purchasing used equipment, your lab reduces raw material usage.

• Access to quality equipment: The cost savings allow labs with minimal funding to acquire high-quality equipment to benefit from advanced technology. Used instruments from reputable suppliers like New Life Scientific have long remaining service lives, helping you get the most out of your investment.

• Lab scalability: With access to more equipment, labs can scale their operations to move their science forward. Work acquiring more devices into your budget with dependable products that fulfill essential roles in your lab.

What to Look for in Used Microcentrifuges

When shopping for a microcentrifuge, look for a digital timer, an automatic start and stop timer, a high-quality motor brake and overload protection. These features will simplify using the device in your laboratory. Factors to look for in used microcentrifuges include:

• Rotor condition: Microcentrifuges use a rotor to drive the device's speed and efficiency. Ensure that the rotor and accessories are in good condition before you purchase a microcentrifuge.

• Warranty: A warranty on used equipment gives you peace of mind. At New Life Scientific, we offer a 90-day warranty to fix or replace equipment if needed.

• Safety features: Microcentrifuges have additional safety features to lower operational risks. These include lid drop protection, imbalance detection, ventilation and exposure protection that keeps researchers safe in case of spills in the chamber.

• Appearance: Do a physical check to ensure the device has only superficial damage, if any. 

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Equipment From Top Microcentrifuge Manufacturers 

New Life Scientific buys and sells high-quality used benchtop microcentrifuges from a range of trusted manufacturers. These brands manufacture microcentrifuges that assist with numerous lab functions, from enzyme kinetics to nucleic acid purification, microscale research and experiments, and other tasks.

ThermoFisher Scientific

ThermoFisher Scientific designs microcentrifuges with a compact footprint. These are ideal for nucleic acid minipreps, microtube processing and hematocrit capillaries.

Eppendorf

This manufacturer produces whisper-quiet microcentrifuges with multi-purpose capabilities well-suited for smaller laboratories. Their reputation in reliability spans over 75 years, and New Life Scientific offers various used Eppendorf microcentrifuge options.

Beckman Coulter

Since 1935, Beckman Coulter has manufactured laboratory equipment with innovation and accuracy. We sell used Beckman Coulter microcentrifuges to complement various micro-volume protocols and sample processing needs for clinical applications.

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Why Buy Microcentrifuges From New Life Scientific?

New Life Scientific stocks used refrigerated and benchtop microcentrifuges. All top-tier products are pre-tested and certified, making us the trusted name in used laboratory equipment. We have a 24-hour or faster response time on all queries. Place your order online now or reach out to our team for assistance with your purchase.

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